Abstrak:
Biofilms are often present on the surface of chronic wounds that inhibit the wound healing process and can cause various other infectious complications. Methanesulfonic acid (MSA) has antimicrobial properties that can disrupt the integrity of biofilms and increase the effectiveness of antibiotic therapy so that it can eliminate the negative effects of biofilms in the healing process of chronic wounds that are difficult to heal. This case study aims to see the effectiveness of methanesulfonic acid (MSA) in overcoming biofilms and its impact on the wound healing process. Method the case study was conducted on a 61-year-old male patient with a chronic diabetic foot wound that had not closed for 3 months, and a 49-year-old female patient with a chronic diabetic foot wound that had not changed for 7 months. The treatment was carried out 3 times, where Methanesulfonic Acid (MSA) was applied to the wound surface for 60 seconds then rinsed with gentle antiseptic, the wound was closed using modern dressing. Evaluation using BWAT which focuses on the amount of exudate, wound size and percentage of granulation. Results based on the evaluation results during 3 treatments, the results obtained biofilm disappeared and the amount of exudate that was previously large was reduced to moderate, the size of the wound was reduced and the percentage of granulation increased where these results were able to be an important factor in achieving the wound healing process that was previously stagnant. Conclusion chronic wounds that are difficult to heal and experience failure of the wound healing process, one of which is caused by biofilm, can be overcome by using Methanesulfonic Acid (MSA) by reducing the negative impact of biofilm on the wound healing process.
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